The cell growth surface treatment on the TPP Tissue Culture Plates is limited to the well bottoms and offers optimal attachment and growth for the most varied types of cell lines. Serrated areas on the sides of the plate and a slight excess in lid width make these plates easy to pick-up and facilitate lid removal. A unique air-extraction, ventilation feature on the plate and lid maximizes external/internal gas exchange and considerably reduces media evaporation without altering the CO2 diffusion. The rings on the lid prevent cross-contamintation from displacement of the individual well condensates.